What is jMRUI?

jMRUI is a software package for advanced time-domain analysis of magnetic resonance spectroscopy (MRS) and spectroscopic imaging (MRSI) data. Through a user-friendly graphical interface biomedical researchers and clinical radiologists can use state-of-the-art signal processing algorithms to analyse and quantify spectroscopic data: from a single spectrum to a full multidimensional MRSI dataset.

The software interfaces algorithms for frequency selective filtering of signals (e.g., removal of residual water), correction of eddy-current artifacts, Cadzow signal-to-noise enhancement, linear prediction, non-linear fitting (quantitation of metabolites), and many more, all of them working in the time-domain to overcome the problems arising from FFT-processed data.

Additionally, jMRUI has a modular design that facilitates the development of plugins to further extend the core capabilities of the software; for instance to interact with PACS servers, to classify spectra, to simulate metabolite basis sets, etc.

Current version

The current version is jMRUI 5.2 relased on 25th May 2015. This version requires Java 1.6 or newer and runs on Microsoft Windows® XP/Vista/7 and GNU/Linux®, 32- and 64-bits.

jMRUI v. 5.0 - Human brain MRSI quantitation
Metabolite quantitation in human brain MRSI with QUEST. The spectra were acquired at 1.5 T with TE of 150 ms. The long TE caused this data set to display a few peaks only, which were fitted in time-domain with QUEST using a simulated basis set of 3 metabolites: N-acetylaspartate, creatine and choline.

License terms and cost

jMRUI is proprietary software distributed under its own license terms, and made freely available to registered users for non-commercial use.

Who uses it?

To date, more than 2500 researchers working on 458 hospital and clinics and  1037 universities in 68 countries worldwide have licensed jMRUI and the number keeps growing. Licensees include spectroscopists, radiologists, physicists, biochemists and engineers from the most reputed research and clinical institutions in the world.

As of October 2014, a search for “jMRUI magnetic resonance” in Google Scholar returns about 2280 references excluding patents and citations.